Yui started out her career as a child actor at age 3. At age 4, she started playing piano, and her talent was discovered by film director Shunji Iwai at age 8, where she played incidental music for his film Love Letter. Throughout the years, she has played for two more of his films, All About Lily Chou-Chou and Hana and Alice.
Yui debuted as a voice actress in April 2005 as Sakura, the main character of TSUBASA CHRoNiCLE, while at the same time she pre-debuted as a singer with "Omna Magni", the ending theme song for Genesis of Aquarion. In August, she debuted as a singer with "Amrita", which was the theme song for TSUBASA CHRoNiCLE the Movie: The Princess in the Birdcage Kingdom. Since then, she has continued on to sing theme songs for animes such as "Undine" for ARIA The ANIMATION, "Euforia" for ARIA The NATURAL, "Sketchbook wo Motta Mama" for Sketchbook ~full color's~, "Synchronicity" for TSUBASA CHRoNiCLE: TOKYO REVELATIONS OVAs, "Spirale" for ARIA The ORIGINATION, and Sasayaki wa "Crescendo" for Francesca, to name a few.
Yui became active in events overseas starting from 2007, where she performed in Beijing as a Japanese ambassador for a Japanese-Chinese cultural exchange business event. In 2009, Yui performed in France at Japan Expo, the world's largest Japan pop culture festival, as the first Japanese Seiyu, and continued on to perform in New York, Shanghai, Singapore and Seoul.
Yui has released "88 Flight" digitally, and "Kimi no Erabu Michi" in 2015, her 10-year anniversary from her debut. She held her anniversary concert at AKASAKA BLITZ, which can be seen in her DVD Yui Makino 10th Anniversary Live~So Happy!!~. She was also engaged worldwide, and attended events in Vietnam, Canada, Bangkok, Singapore, China, and Hong Kong. In July, she performed her solo concert in Hong Kong to a sold out crowd. She released her fourth studio album "Tabi＊Note" in October, and continues to perform worldwide, attracting many with her broad and diverse talents.